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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11348 |
G907
|
Antibiotic | Microbiology/Virology |
G907 是一种具有选择性和有效性的小分子ATP 结合盒 (ABC) 转运蛋白 MsbA 的拮抗剂,具有杀菌活性,可将 MsbA 捕获在朝内的脂多糖中。 G907 对大肠杆菌 MsbA 有抑制作用, IC50 值为 18 nM。 | |||
T73935 | MsbA-IN-6 | Antibiotic | Microbiology/Virology |
MsbA-IN-6作为一种高效的抑制剂,针对革兰氏阴性ATP结合盒(ABC)转运蛋白MsbA具有抗生素作用。MsbA是关键的内膜蛋白,负责将脂多糖从内叶转运至内膜的周质面。MsbA-IN-6通过抑制大肠杆菌MsbA的ATP酶与转运活性实现其杀菌效果,并对多种临床上常见的多药耐药菌株保持有效活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02204 |
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding prot... |
Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... | |||
TMPK-01242 |
MD2/LY96 Protein, Human, Recombinant (His)
MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1 |
Human | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1. | |||
TMPK-00632 |
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2 |
Cynomolgus | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. | |||
TMPY-02908 |
BPI Protein, Human, Recombinant (His)
BPIFD1,bactericidal/permeability-increasing protein... |
Human | HEK293 Cells |
Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonuclear leukocytes. Bactericidal/permeability-increasing protein also is a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. Bactericidal/permeability-increasing protein contains two domains t... | |||
TMPY-04391 |
Lyn Protein, Human, Recombinant (GST)
JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p... |
Human | Baculovirus Insect Cells |
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif... |