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Search Results for " lipopolysaccharide binding protein "
Targets Recommended: Antibiotic

2

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11348 G907

Antibiotic Microbiology/Virology
G907 是一种具有选择性和有效性的小分子ATP 结合盒 (ABC) 转运蛋白 MsbA 的拮抗剂,具有杀菌活性,可将 MsbA 捕获在朝内的脂多糖中。 G907 对大肠杆菌 MsbA 有抑制作用, IC50 值为 18 nM。
T73935 MsbA-IN-6

Antibiotic Microbiology/Virology
MsbA-IN-6作为一种高效的抑制剂,针对革兰氏阴性ATP结合盒(ABC)转运蛋白MsbA具有抗生素作用。MsbA是关键的内膜蛋白,负责将脂多糖从内叶转运至内膜的周质面。MsbA-IN-6通过抑制大肠杆菌MsbA的ATP酶与转运活性实现其杀菌效果,并对多种临床上常见的多药耐药菌株保持有效活性。

化合物

G907
Cat.No: T11348
Synonym:
Target: Antibiotic
MsbA-IN-6
Cat.No: T73935
Synonym:
Target: Antibiotic
Cat. No. Product Name Species Expression System
TMPY-02204 LBP Protein, Human, Recombinant (His)

BPIFD2,lipopolysaccharide binding prot...

Human HEK293 Cells
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end...
TMPK-01242 MD2/LY96 Protein, Human, Recombinant (His)

MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1

Human E. coli
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1.
TMPK-00632 MD2/LY96 Protein, Cynomolgus, Recombinant (His)

ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2

Cynomolgus E. coli
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0.
TMPY-02908 BPI Protein, Human, Recombinant (His)

BPIFD1,bactericidal/permeability-increasing protein...

Human HEK293 Cells
Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonuclear leukocytes. Bactericidal/permeability-increasing protein also is a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. Bactericidal/permeability-increasing protein contains two domains t...
TMPY-04391 Lyn Protein, Human, Recombinant (GST)

JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...

Human Baculovirus Insect Cells
Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...

重组蛋白

LBP Protein, Human, Recombinant (His)
Cat.No: TMPY-02204
Species: Human
Expression System: HEK293 Cells
MD2/LY96 Protein, Human, Recombinant (His)
Cat.No: TMPK-01242
Species: Human
Expression System: E. coli
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00632
Species: Cynomolgus
Expression System: E. coli
BPI Protein, Human, Recombinant (His)
Cat.No: TMPY-02908
Species: Human
Expression System: HEK293 Cells
Lyn Protein, Human, Recombinant (GST)
Cat.No: TMPY-04391
Species: Human
Expression System: Baculovirus Insect Cells
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